Jun 24, 2021 · Combined with BioMEMS or microfluidics, miniaturized microfluidic PCR has become one of important directions of PCR technology. By utilizing the advantages of microfluidics, rapid PCR can be performed in such a portable device with high convenience, which is highly desired in POC diagnostics.
May 10, 2016 · (2016, May 10). Enhancing lab-on-a-chip peristalsis with electro-osmosis: Researchers have conducted analyses to electrically increase liquid flow in pump-free microfluidic devices. ScienceDaily
Here, we developed a pump-free microfluidic device that enables rapid mixing by combining paper and plastic. The device was fabricated by laminating transparency film and double-sided adhesive and is composed of an overlapping inlet ending in a paper-based reaction area.
Oct 22, 2013 · Read "Bubble-driven mixer integrated with a microfluidic bead-based ELISA for rapid bladder cancer biomarker detection, Biomedical Microdevices" on DeepDyve, the largest online rental service for scholarly research with thousands of academic publications available at your fingertips.
Aug 03, 2010 · The combined mixing time enhancement is, therefore, a factor of 125,000. In the flat Y-mixer shown here, full mixing is achieved after ~2.5 mm of paper layer contact. For a measured flow velocity of 0.01 cm s −1, this corresponds to a mixing time of 2.5 seconds.
Request PDF | Design and application of a self-pumping microfluidic staggered herringbone mixer | The rapid mixing of reagents is critical to a wide range of chemical and biological reactions but
Jun 27, 2016 · This paper proposes a new "twisted" 3D microfluidic mixer fabricated by a laser writing/microfabrication technique. Effective and efficient mixing using the twisted micromixers can be obtained by combining two general chaotic mixing mechanisms: splitting/recombining and chaotic advection. The lamination of mixer units provides the splitting and recombination mechanism when …
Jan 19, 2021 · The final flow-based microfluidic gradient mixer is successful and allows water infused with green and red dye to flow through the channels without leaking (Fig. 5b). The time it takes to engrave, shrink, and adhere the MFC prototype is less than an hour, which is promising compared to current lithographic and non-lithographic fabrication methods.
Microfluidic mixer short review: all there is to know
Feb 05, 2008 · Wang, Y, Zhe, J, Dutta, P, & Cheng, GJ. "A Hybrid Rapid Microfluidic Mixer Utilizing Electrokinetic Relay and Asymmetric Flow Geometries for Lab-on-a-Chip Applications." Proceedings of the ASME 2005 International Mechanical Engineering Congress and Exposition. Microelectromechanical Systems. Orlando, Florida, USA. November 5–11, 2005. pp. 233
Accessories. Fluigent's broad range of solutions for use in microfluidic and nanofluidic applications offer greater control, automation, precision, and ease of use. If you are seeking to replace high-precision syringe pumps or other conventional instruments, we offer modern microfluidic systems and components that enhance productivity.
Jan 01, 2012 · Results Microfluidic mixing results in production of monodisperse LNP. The SHM provides a means of reproducible and very rapid mixing of two input streams using microstructure-induced chaotic advection 17 at intermediate Reynolds number (2 < Re < 500). Following the combination of two fluid streams they pass through a series of herringbone structures that induce rotational flow …
Jan 31, 2013 · INTRODUCTION. Integrated microfluidic devices have been used in research labs for over twenty years 1 and within the last decade their use in life science research has increased dramatically in large part because of the invention of soft lithography 2 and microfluidic large scale integration. 3 These technological advances have increased the throughput of device production, improved rapid
The latter disadvantage of free magnetic beads is resolved by magnetic artificial cilia that, being connected to the walls of the microfluidic chip, form an integral part of the device. The artificial cilia, next to induce mixing, can be used also to pump liquids or even to transport particles or cells in microfluidic …
Nov 23, 2016 · The resultant µTesla pumps were coupled magnetically to a lab stirring plate to provide rotor actuation up to 1200 rpm, where it achieved a pump pressure of 253 Pa and maximum flow greater than 12 mL/min. Coupling this µTesla pump to a microchannel mixer with Tesla-valve inspired geometries generated gradients using color dyes.
PI: Juan G. Santiago. We are developing rapid microfluidic mixers for a variety of assays including studies of the kinetics of protein folding and enzymatic reaction rates. Specifically, we are developing planar microfluidic devices that leverage flow structures for 3D hydrodynamic focusing to decrease the characteristic time scale for mixing
In general, cationic liposomes of defined size can be manufactured by microfluidic rapid mixing through carefully tuning the manufacturing process parameters. Thus, homogeneous lipoplex suspensions in a size range from 20 to 100 nm can be produced by adjusting the total flow rate and the flow rate ratio ( i.e. the ratio between the organic
Aug 21, 2015 · Ahmed et al combined acoustic waves with a microfeature to create a fast bubble mixer within a microchannel . The first step in creating this type of mixer was to design a horseshoe shape within a channel between two fluids, opening in the same direction as the flow direction (figure 7(c) ).
Download Free PDF. Download Free PDF. A Microfluidic Mixer Utilizing Electrokinetic Relay Switching and Asymmetric Flow Geometries. Journal of Fluids Engineering, 2007. Remotely powered distributed microfluidic pumps and mixers based on miniature diodes. By Dimiter Petsev.
Mar 19, 2021 · The rapid mixing of reagents is critical to a wide range of chemical and biological reactions but is difficult to implement in microfluidic devices, particularly in capillary action/passive pumping devices or in point-of-need environments. Here, we develop a self-pumping asymmetric staggered herringbone mixer made from only laser-ablated glass and tape. This lab-on-a-chip platform …
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